Sex differences in response to ketamine as a rapidly acting intervention for treatment resistant depression.

/in /by

Freeman MP1, Papakostas GI2, Hoeppner B2, Mazzone E2, Judge H2, Cusin C2, Mathew S3, Sanacora G4, Iosifescu D5, DeBattista C6, Trivedi MH7, Fava M2.

 2019 Jan 8;110:166-171. doi: 10.1016/j.jpsychires.2019.01.010.

Sex Differences in Response to Ketamine as A Rapidly Acting Intervention for Treatment Resistant Depression

/in /by

Marlene P.Freemana | George Papakostasa | Bettina Hoeppnera | Erica Mazzonea | Heidi Judgea | Cristina Cusina | Sanjay Mathew | Gerard Sanacorac | Dan Iosifescud | Charles DeBattistae | Madhukar H.Trivedif | Maurizio Favaa

Received 19 September 2018, Revised 3 January 2019, Accepted 7 January 2019, Available online 8 January 2019.

Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD).

/in /by

Fava M, Freeman MP, Flynn M, Hoeppner BB, Shelton R, Iosifescu DV, Murrough JW, Mischoulon D, Cusin C, Rapaport M, Dunlop BW, Trivedi MH, Jha M, Sanacora G, Hermes G, Papakostas GI.

Brain Stimul. 2018 Jan – Feb;11(1):75-84. doi: 10.1016/j.brs.2017.09.010. Epub 2017 Sep 23.

Efficacy of Brexpiprazole as Adjunctive Treatment in Major Depressive Disorder With Irritability: Post Hoc Analysis of 2 Pivotal Clinical Studies.

/in /by

Fava M, Weiller E, Zhang P, Weiss C.

J Clin Psychopharmacol. 2017 Apr;37(2):276-278. doi: 10.1097/JCP.0000000000000678. No abstract available.

Augmentation in OCD Patients Resistant to Selective Serotonin Reuptake Inhibitors: A Proof-of-Concept, Randomized, Placebo-Controlled, Phase 2 Study.

/in /by

Rutrick D, Stein DJ, Subramanian G, Smith B, Fava M, Hasler G, Cha JH, Gasparini F, Donchev T, Ocwieja M, Johns D, Gomez-Mancilla B. Mavoglurant

Adv Ther. 2017 Feb;34(2):524-541. doi: 10.1007/s12325-016-0468-5. Epub 2017 Jan 2.

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.

/in /by

Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP.

Mol Psychiatry. 2016 Oct;21(10):1483-4. doi: 10.1038/mp.2016.140. No abstract available.

Major depressive disorder.

/in /by

Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A, Fava M, Mohr DC, Schatzberg AF.

Nat Rev Dis Primers. 2016 Sep 15;2:16065. doi: 10.1038/nrdp.2016.65.

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression.

/in /by

Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, Van Nueten L.

Am J Psychiatry. 2016 Aug 1;173(8):816-26. doi: 10.1176/appi.ajp.2016.16010037.

Health-related quality of life in acute schizophrenia patients treated with RBP-7000 once monthly risperidone: An 8-week, randomized, double-blind, placebo-controlled, multicenter phase 3 study.

/in /by

Isitt JJ, Nadipelli VR, Kouassi A, Fava M, Heidbreder C.

Schizophr Res. 2016 Jul;174(1-3):126-31. doi: 10.1016/j.schres.2016.03.020.