A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.
Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP.
Mol Psychiatry. 2015 Dec 8. doi: 10.1038/mp.2015.178. [Epub ahead of print]
Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder.
Papakostas GI, Ionescu DF.
Mol Psychiatry. 2015 Oct;20(10):1142-50. doi: 10.1038/mp.2015.92. Epub 2015 Jul 7. Review.
The Role of Anger/Hostility in Treatment-Resistant Depression: A Secondary Analysis From the ADAPT-A Study.
Fisher LB, Fava M, Doros GD, Alpert JE, Henry M, Huz I, Freeman MP
J Nerv Ment Dis. 2015 Oct;203(10):762-8. doi: 10.1097/NMD.0000000000000364.
The role of regulators, investigators, and patient participants in the rise of the placebo response in major depressive disorder. World Psychiatry.
Fava M.
2015 Oct;14(3):307-8. doi: 10.1002/wps.20247.
A Novel Methodology to Estimate the Treatment Effect in Presence of Highly Variable Placebo Response.
Gomeni R, Goyal N, Bressolle F, Fava M.
Neuropsychopharmacology. 2015 Oct;40(11):2588-95.
Changes in cognitive symptoms after a buspirone-melatonin combination treatment for Major Depressive Disorder.
Targum SD, Wedel PC, Fava M.
J Psychiatr Res. 2015 Sep;68:392-6. doi: 10.1016/j.jpsychires.2015.04.024. Epub 2015 May 9.
The American Society of Clinical Psychopharmacology survey of psychopharmacologists’ practice patterns for the treatment of mood disorders. Depress Anxiety.
Goldberg JF, Freeman MP, Balon R, Citrome L, Thase ME, Kane JM, Fava M.
2015 Aug;32(8):605-13. doi: 10.1002/da.22378. Epub 2015 Jun 30.
Antidepressants and their effect on cognition in major depressive disorder.
Papakostas GI.
J Clin Psychiatry. 2015 Aug;76(8):e1046. doi: 10.4088/JCP.13086tx5c. Review.
Placebo non-response measure in sequential parallel comparison design studies.
Rybin D, Doros G, Pencina MJ, Fava M.
Stat Med. 2015 Jul 10;34(15):2281-93. doi: 10.1002/sim.6494. Epub 2015 Apr 10.
Evaluation of opioid modulation in major depressive disorder.
Ehrich E, Turncliff R, Du Y, Leigh-Pemberton R, Fernandez E, Jones R, Fava M.
Neuropsychopharmacology. 2015 May;40(6):1448-55. doi: 10.1038/npp.2014.330. Epub 2014 Dec 18.
© 2024 Copyright MGH Clinical Trials Network and Institute.
Website design by Tomo360